![]() ![]() A total of 4761 SCM cases were identified, with a median age of 66 years. SCM cases were sampled from the Surveillance, Epidemiology and End Results (SEER) Program (1973‑2017). The aim of the present study was to investigate the incidence of SCM, its general demographics, basic clinico‑pathologic features, treatment outcomes and disease‑specific prognostic factors. Spindle cell melanoma (SCM) is a rare morphological subtype of melanoma, which is relatively uncharacterized. This system, based on measurements of lesion reflectance (i.e., the fraction of light reflected or diffusedīy a pigmented lesion), provides an objective evaluation of color of skin lesion. In the context of another study on pigmented lesions still ongoing at our institution, sixteen of our cases of PSCN were alsoĪnalyzed by a telespectrophotometric system in vivo before surgery. well-defined versus ill-defined bordersĪlso recorded were the main dermatoscopic features and the diagnoses performed by ELM.presence of a raised component on the skin surface.The following gross morphological attributes were abstracted from the clinical records: Distribution of 63 pigmented spindle cell nevi according to site and gender Site The patients ranged from 5 to 62 years, with a The distribution of cases according to site and gender is shown in Table 1. Monocular microscope equipped with an achromatic lens permitting a magnification of 10×. Īll lesions had a recorded clinical diagnosis that has been coupled with ELM evaluation. ThoseĬases, all examined clinically and then excised under local anesthesia in our institute, met the features regarded as histologicalĬharacteristics of PSCN according to widely accepted criteria. In total, 63 lesions in 63 patients (43 females and 20 males) were selected. Cases submitted for consultation, cases with diagnostic uncertainty, orĬases recoded as Spitz nevi were excluded. It evaluates the improvement led by ELM in the diagnosis of this lesion in order to reduce the number of diagnostic operationsĪll patients with histologic diagnosis of PSCN observed at the Istituto Nazionale per lo Studio e la Cura dei Tumori of Milanįrom January 1994 to December 1998 were evaluated. This study presents a clinical and dermoscopic description of 63 consecutive cases of PSCN observed and excised at our institute. Of morphological features not visible to the naked eye, which enhances the clinical diagnosis of nearly all the pigmented This tumor to be a separate clinical entity from Spitz nevus, and so we chose to focus our interest on its clinical features.Įpiluminescence Microscopy (ELM), a noninvasive technique employed in the clinical diagnosis of pigmented skin lesions, permitsĪ detailed examination of the pigmented structures of the epidermis and dermoepidermal junction. PSCN has clinical and histopathologic features that may create difficulty in differentiating it from melanoma. It is generally considered a separate clinicopathologic entity, even if some authors classify this nevus as a variant of Pigmented spindle-cell nevus (PSCN) is a benign melanocytic lesion first described by Reed et al. ![]() Melanoma simulators, those entities that may be clinically and sometimes histologically confused with melanoma. These issues are particularly evident when considering Major surgery in cases where benign lesions show doubtful features. Of the clinician of missing an early curable melanoma conflicts with his or her desire to avoid unnecessary minor or even clinical differential diagnosis of melanoma presents a formidable challenge even to experienced physicians. Pigmented spindle-cell nevus: A melanoma simulatorĪndrea Maurichi MD 1, Marzia Baldi MD 1, Cesare Bartoli MD 2, Aldo Bono MD 1, Tiziana Camerini PhD 3, Daniele Moglia MD 1, Roberto Patuzzo MD 1, Elisabetta Pennacchioli MD 1, Gabrina Tragni MD 4, Mario Santinami MD 1 Dermatology Online Journal 10 (2): 5 Melanoma Unit 1, Day Surgery Unit 2, Controlled Clinical Trials Unit 3, Pathology and Cytopathology Unit 4, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy. ![]()
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